Origins of anterior-posterior polarity by localized activation of Disheveled
نویسندگان
چکیده
منابع مشابه
Polarity establishment requires localized activation of Cdc42
Establishment of cell polarity in animal and fungal cells involves localization of the conserved Rho-family guanosine triphosphatase, Cdc42, to the cortical region destined to become the "front" of the cell. The high local concentration of active Cdc42 promotes cytoskeletal polarization through various effectors. Cdc42 accumulation at the front is thought to involve positive feedback, and studi...
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In Drosophila melanogaster, nanos functions as a localized determinant of posterior pattern. Nanos RNA is localized to the posterior pole of the maturing egg cell and encodes a protein that emanates from this localized source. Nanos acts as a translational repressor and thereby establishes a gradient of the morphogen Hunchback. Here we show that the mechanism by which nanos acts in Drosophila i...
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Origins of Cell Polarity
ing proteins assembles at the site marked by the cue, *Department of Molecular and Cell Biology then a polarized actin and septin cytoskeleton assemUniversity of California, Berkeley bles, and the secretory apparatus becomes oriented Berkeley, California 94720 toward the spatial cue. Considerable information about †Department of Molecular and Cellular Physiology bud formation has been obtained ...
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ژورنال
عنوان ژورنال: Molecular Reproduction and Development
سال: 2017
ISSN: 1040-452X
DOI: 10.1002/mrd.22839